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Temple, natural killer (NK)-cell, and lymphokine-activated killer (LAK)-cell function Cell type T cells Functional effect Peripheral lymphopenia Decreased circulating T-cell numbers Loss of suppressor T cells Downregulated CD4 and CD45RA expression Impaired mitogen responsiveness Impaired lymphokine production Cutaneous anergy to recall and de novo antigens Inhibitors of lymphoid activation Decreased blood CD8CD4 ratio Bronchoalveolar lavage (BAL) lymphocytic alveolitis Decreased BAL CD8CD4 ratio Impaired blood andor BAL 3taps forex factory activity Impaired LAK cell activity References 21,3133 21,3135 20 26 1821 22 18,23,24 18,25 33,34 32,3537 32,36,37 38,4042 39 NK cells LAK cells Tumor-Infiltrating Lymphocytes (TIL) in Mesothelioma Lymphocytic infiltrates are not usually prominent within the stroma of mesothelioma biopsies and there are few reports of their possible sig- nificance.
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